Doctor's Best utilizes only the highest quality Italian Soloesse® SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse® SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.

Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.

Supplementing with SAM-e

Soloesse® Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate bio-chemical activity in the human body.

SAM-e and Mood and Cognitive Function

SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Liver Function

SAM-e helps support healthy levels of glutathione, a critical anti-oxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

Double Strength SAM-e is sealed in blister packs for freshness and stability.

Serving Instructions

Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet

Serving Size

One tablet contains:

Ingredients

SAM-e   400 mg
(S-Adenosyl-L-Methionine disulfate p-toluensulfonate)

Other Ingredients

Microcrystalline cellulose

Stearic acid
Calcium chloride anhydrous
magnesium silicate
Magnesium stearate
Magnesium hydroxide
Flake shellac dewaxed
Glycerol
Silica
Arginine base
Sodium alginate
Calcium oxide